Case Studies

All Urban Solutions and Sustainability Health and Biomedical Sciences Advanced Manufacturing and Engineering
Harnessing High Performance Computing (HPC) for Breakthroughs in Cancer Genomics
Urban Solutions and Sustainability,
Harnessing High Performance Computing (HPC) for Breakthroughs in Cancer Genomics

MERaLiON (Multimodal Empathetic Reasoning and Learning in One Network), a programme led by A*STAR Institute for Infocomm Research (A*STAR I²R), develops advanced Multimodal Large Language Models (MLLMs) to…

MERaLiON: Advancing Multimodal AI for Singapore’s Future in Language Processing
Urban Solutions and Sustainability,
MERaLiON: Advancing Multimodal AI for Singapore’s Future in Language Processing

MERaLiON (Multimodal Empathetic Reasoning and Learning in One Network), a programme led by A*STAR Institute for Infocomm Research (A*STAR I²R), develops advanced Multimodal Large Language Models (MLLMs) to…

Dispersion Analysis for Handling Maritime New Fuels
Urban Solutions and Sustainability,
Dispersion Analysis for Handling Maritime New Fuels

31 December 2024

Leveraging Supercomputing Resources for Net-Zero Research & Development
Urban Solutions and Sustainability,
Leveraging Supercomputing Resources for Net-Zero Research & Development

Researchers from NUS are proposing a privacy-preserved data fusion algorithm for traffic state estimation (FedTSE) to facilitate collaboration and data sharing between multiple data owners…

Taking a stratified approach to the prevention of Type 2 diabetes in the Asian population
Health and Biomedical Sciences,
Taking a stratified approach to the prevention of Type 2 diabetes in the Asian population

Researchers from Nanyang Technological University (NTU) and their collaborators are investigating the molecular regulatory disturbances underlying development of Type 2 diabetes amongst Asian populations.

Privacy-Preserving Data Fusion for Traffic State Estimation
Urban Solutions and Sustainability,
Privacy-Preserving Data Fusion for Traffic State Estimation

Researchers from NUS are proposing a privacy-preserved data fusion algorithm for traffic state estimation (FedTSE) to facilitate collaboration and data sharing between multiple data owners…

Accelerating the discovery of new 2D materials using HPC
Advanced Manufacturing and Engineering,
Accelerating the discovery of new 2D materials using HPC

New 2D materials are being discovered every day. At the NUS Centre for Advanced 2D Materials (CA2DM), researchers have been building up a database of 6,000 candidate 2D…

Tailoring brain tumour treatments for better patient outcomes
Health and Biomedical Sciences,
Tailoring brain tumour treatments for better patient outcomes

Doctors and researchers at the National Neuroscience Institute (NNI) are using a supercomputer to analyse the brain tumour genome of individual patients. The data could…

Building an enzyme library and the tools to decipher their functions
Health and Biomedical Sciences,
Building an enzyme library and the tools to decipher their functions

The Enzyme Function Initiative (EFI) is a large-scale collaborative project looking at charting and compiling a database of enzymes functions. NUS’ SINERGY is now part of the…

The Asian genome is one of the most diverse but least studied
Health and Biomedical Sciences,
The Asian genome is one of the most diverse but least studied

With the help of supercomputing resources from NSCC, researchers from the GenomeAsia 100K project published the data in the Nature journal. The study also highlighted the…

Supercomputer sequences genome of Singapore’s multi-ethnic Asian population
Health and Biomedical Sciences,
Supercomputer sequences genome of Singapore’s multi-ethnic Asian population

The analysis of this genetic data helps researchers expand the understanding of the biology of diseases that affect Singaporeans. A new study – said to be the largest…

Ambitious project to map the human brain by 2024
Health and Biomedical Sciences,
Ambitious project to map the human brain by 2024

Synchrotron for Neuroscience – an Asia Pacific Strategic Enterprise (SYNAPSE) is an international project that is aiming to create a comprehensive ultra-high resolution 3D map of…

Urban planning simulation tool based on HPC technology wins President’s Technology Award (PTA)
Urban Solutions and Sustainability,
Urban planning simulation tool based on HPC technology wins President’s Technology Award (PTA)

Using the ASPIRE 1 supercomputer, the tool was used to create a complete three-dimensional (3D) air flow simulation encompassing Singapore’s built environment. A research team…

Enhancing oil recovery techniques for the oil and gas industry
Health and Biomedical Sciences,
Enhancing oil recovery techniques for the oil and gas industry

Developing advanced functional polymer particles for enhanced flow assurance through the use of NSCC’s supercomputing resources. Around 60% of oil deposits remain unrecovered in…

Making better streamlines – Stability analysis and numerical simulations of complex flows
Advanced Manufacturing and Engineering,
Making better streamlines – Stability analysis and numerical simulations of complex flows

Leveraging NSCC’s supercomputing resources to unravel the underlying physics in complex flows. The study of flow instability determines how an undisturbed flow transitions to…

Mapping the evolution of the 500 million year-old horseshoe crab
Health and Biomedical Sciences,
Mapping the evolution of the 500 million year-old horseshoe crab

The genomic study of the horseshoe crab, which was done using NSCC’s supercomputing resources, can help in the conservation of the horseshoe crab and decipher its remarkably…

Simulating combustion processes in marine engines to reduce carbon footprint
Advanced Manufacturing and Engineering,
Simulating combustion processes in marine engines to reduce carbon footprint

Using supercomputers to study the various aspects of fuel utilisation in shipping helps combat pollution The drive for enhanced energy efficiency, lower pollution and…

Ecologically engineering Singapore’s seawalls to enhance biodiversity
Advanced Manufacturing and Engineering,
Ecologically engineering Singapore’s seawalls to enhance biodiversity

Tapping on NSCC’s supercomputing resources to preserve ecosystems and strengthen natural resilience Due to extensive land reclamation, much of Singapore’s original coastal…

A cough goes a long way – Understanding the spread of airborne cough droplets
Health and Biomedical Sciences,
A cough goes a long way – Understanding the spread of airborne cough droplets

Studying the dispersion of droplets in environmental transmission using supercomputers is helping researchers better understand what happens when a person coughs, in order to…

High resolution modelling of weather and climate over Singapore and Southeast Asia
Advanced Manufacturing and Engineering,
High resolution modelling of weather and climate over Singapore and Southeast Asia

Using NSCC’s supercomputing resources, researchers in Singapore are using complex computer models to look at how climate and weather impact the region The latest climate…

Stemming mosquito-borne disease outbreaks with the help of supercomputers
Health and Biomedical Sciences,
Stemming mosquito-borne disease outbreaks with the help of supercomputers

Tapping NSCC’s supercomputer to support the surveillance and control of vector-borne and environment-related diseases like dengue in Singapore. In July, the number of dengue…

Tracking down human cancer mutations using supercomputers
Health and Biomedical Sciences,
Tracking down human cancer mutations using supercomputers

Researchers employ NSCC’s supercomputer to better understand mutational signatures in human cancers and to explore ways to reduce the risk of cancer. Mutagenesis is a major cause…

Reducing the risk of fires with the help of supercomputers
Advanced Manufacturing and Engineering,
Reducing the risk of fires with the help of supercomputers

Unlocking the interactive physics in two-phase chemically reacting flows with NSCC’s high performance computing resources to mitigate fires in buildings and enclosed spaces. Fire…

Developing new diabetes screening and monitoring methods using HPC
Health and Biomedical Sciences,
Developing new diabetes screening and monitoring methods using HPC

Researchers employ NSCC’s supercomputer and high performance computing (HPC) to monitor glucose levels in diabetes patients and to explore ways to reduce the risk of diabetes….

Balancing skin bacterial composition for healthier skin
Health and Biomedical Sciences,
Balancing skin bacterial composition for healthier skin

NSCC’s supercomputer help analyse the Asian skin microbiome in order to develop products to improve skin treatments and maintain skin health. Our skin harbours a complex…

Better AI for safer self-driving
Advanced Manufacturing and Engineering,
Better AI for safer self-driving

Strengthening the safety and robustness of AI in self-driving vehicles using NSCC’s high performance computing resources. Artificial Intelligence (AI) technologies are gaining…

Using HPC to help conserve Southeast Asia’s biodiversity
Health and Biomedical Sciences,
Using HPC to help conserve Southeast Asia’s biodiversity

NSCC’s supercomputer is being used to accelerate the analysis of the evolutionary history and biogeography of ‘ancient’ trapdoor spiders so that they can be used as a model…

High-throughput, data intensive study on male infertility using HPC
Health and Biomedical Sciences,
High-throughput, data intensive study on male infertility using HPC

A team from Duke-NUS Medical School is using supercomputers to aid in the building of a molecular ‘atlas’ for sperm generation to better understand human male infertility and…

Using HPC to better understand psychiatric disorders
Health and Biomedical Sciences,
Using HPC to better understand psychiatric disorders

Researchers from A*STAR leverage NSCC’s supercomputer to stratify illness and subtypes in psychiatric disorders in order to facilitate better diagnosis and monitoring. Mental…

Speeding up the process of materials discovery and development using HPC
Advanced Manufacturing and Engineering,
Speeding up the process of materials discovery and development using HPC

NSCC’s supercomputer helps perform high-throughput computations to accelerate the process of alloy development and to make it more cost effective. Traditional pathways in the…

High performance computing for studying and preserving marine ecosystems
Urban Solutions and Sustainability,
High performance computing for studying and preserving marine ecosystems

The Reef Ecology Lab at NUS leverages NSCC’s supercomputing capabilities for marine genomic analyses to better understand and design solutions for marine conservation in…

Studying the mutation mechanisms of the flu virus to develop better vaccines
Health and Biomedical Sciences,
Studying the mutation mechanisms of the flu virus to develop better vaccines

Utilising high performance computing to understand the life cycle of Influenza A Virus to aid in the development and commercial production of vaccines. Influenza A Virus (IAV) is…

Studying the potential effect of storm surges and tsunamis on coastal regions in the South China Sea
Urban Solutions and Sustainability,
Studying the potential effect of storm surges and tsunamis on coastal regions in the South China Sea

A research team from NUS is harnessing high performance computing to quantify the uncertainty of earthquake characteristics and tropical cyclone storm surges to estimate its…

Using Machine Learning to identify and improve protein-ligand binding affinity predictions
Health and Biomedical Sciences,
Using Machine Learning to identify and improve protein-ligand binding affinity predictions

Researchers from NTU are utilising NSCC’s supercomputing resources to improve the performance of learning models in molecular data analysis. AI is expected to play an…

HPC powers aerodynamic improvements to turbine blades
Advanced Manufacturing and Engineering,
HPC powers aerodynamic improvements to turbine blades

Researchers at NTU are tapping HPC resources to investigate methods to improve turbine blade aerodynamics that could lead to energy and fuel savings. Flow separation is a common…

When is water not just water?
Urban Solutions and Sustainability,
When is water not just water?

NSCC’s supercomputing resource is helping researchers gain a better understanding of the true nature of water, and its properties. Although it is one of the most common elements,…

Automating the detection of defects in recycled solar cells
Advanced Manufacturing and Engineering,
Automating the detection of defects in recycled solar cells

Researchers at NTU are using HPC to automate and more accurately detect visual defects in solar panels in a bid to reduce the workload required for manual inspections. Amid the…

Microclimate modelling research to curb rising temperatures in Singapore
Urban Solutions and Sustainability,
Microclimate modelling research to curb rising temperatures in Singapore

A research team from NUS is tapping on NSCC’s supercomputing resources to develop an urban microclimate model for the local Singapore environment at the NUS Kent Ridge campus…

A quieter way to fly – Reducing jet engine noise through HPC research
Advanced Manufacturing and Engineering,
A quieter way to fly – Reducing jet engine noise through HPC research

Researchers from NUS are harnessing the power of supercomputing to understand the mechanism of noise generated by jet engines to reduce the impact of noise emission on the…

Training conventional surveillance systems to be smarter
Advanced Manufacturing and Engineering,
Training conventional surveillance systems to be smarter

Researchers at NTU are using HPC to design smart and autonomous cameras to aid in digital monitoring and crime prevention. Video surveillance systems have been around for many…

Increasing the effectiveness of antibiotics by analysing antibiotic resistance using supercomputers
Health and Biomedical Sciences,
Increasing the effectiveness of antibiotics by analysing antibiotic resistance using supercomputers

Researchers from NTU are utilising NSCC’s supercomputing resources to understand the permeation of antibiotics in order to design new novel antibiotics. Antibiotic resistance is…

Accelerating research to curb the spread of metastatic cancers
Health and Biomedical Sciences,
Accelerating research to curb the spread of metastatic cancers

Harnessing supercomputers to understand the molecular and cellular processes of metastatic cancers and to develop novel therapeutics targeting the disease. Metastasis, which is…

Harnessing supercomputers to correct quantum errors
Advanced Manufacturing and Engineering,
Harnessing supercomputers to correct quantum errors

Researchers at SUTD and Yale-NUS are tapping HPC resources to study the occurrence of errors in quantum computations and devise models to better correct errors. A quantum…

Curbing the spread of Dengue
Health and Biomedical Sciences,
Curbing the spread of Dengue

Researchers at A*STAR are tapping HPC resources to gain a deeper understanding of the dengue virus in order to design improved therapeutic strategies. Dengue virus (DENV) is a…

Peeking into the lenses of tropical jumping spiders
Health and Biomedical Sciences,
Peeking into the lenses of tropical jumping spiders

Researchers at NUS are tapping HPC resources to gain a deeper understanding on the visual systems of jumping spiders in order to discover how species adapt and diversify. Visual…

Safely using hydrogen as a fuel
Advanced Manufacturing and Engineering,
Safely using hydrogen as a fuel

NUS researchers leveraging supercomputing to explore hydrogen combustion inhibition methods in order to prevent hazards from occurring. In recent years, hydrogen fuel has…

Supercomputer powers research for early detection of heart diseases
Health and Biomedical Sciences,
Supercomputer powers research for early detection of heart diseases

Researchers from A*STAR leverage high performance computing for cardiovascular disease stratification for early diagnosis and prevention. Cardiovascular disease is the leading…

Supercomputers accelerate research to develop more effective cancer immunotherapy
Health and Biomedical Sciences,
Supercomputers accelerate research to develop more effective cancer immunotherapy

A*STAR researchers leverage supercomputing to predict immunotherapy outcomes in order to better select treatments best suited for patients. Immunotherapy is a breakthrough cancer…

Research on ‘greener’ fertiliser production using HPC-powered simulations
Urban Solutions and Sustainability,
Research on ‘greener’ fertiliser production using HPC-powered simulations

Researchers at NTU are tapping HPC resources to derive a process for highly selective urea production in order to reduce carbon emissions. Urea (CO(NH2)2) provides low-cost…

Monitoring the health of trees with supercomputer-enabled deep learning tools
Urban Solutions and Sustainability,
Monitoring the health of trees with supercomputer-enabled deep learning tools

Researchers from NTU leverage high-performance computing to develop tools to assess tree health in order to prevent tree falls. For Singapore’s thriving, lush greenery, the…

Supercomputers help scientists better understand peanut allergies
Health and Biomedical Sciences,
Supercomputers help scientists better understand peanut allergies

Researchers from A*STAR leverage high-performance computing (HPC) resources to develop advanced structural model and simulations of the interactions between antigens and…

Supercomputers aid in research to control ozone pollution
Urban Solutions and Sustainability,
Supercomputers aid in research to control ozone pollution

Researchers from NTU leverage high-performance computing resources to better understand the effects of ozone pollution and develop tools to control emissions in Southeast Asia….

Designing safer nanomaterials and medicines with the aid of supercomputers
Health and Biomedical Sciences,
Designing safer nanomaterials and medicines with the aid of supercomputers

Researchers from Nanyang Technological University leverage high-performance computing resources to better understand the interactions between nanomaterials and biological…

Tackling antibiotic resistance with HPC
Health and Biomedical Sciences,
Tackling antibiotic resistance with HPC

Tackling antibiotic resistance with HPC Antimicrobial resistance (AMR) is a global healthcare issue, which has resulted in 1.27 million deaths in 2019 and is expected to cause 10…

Gaining Deeper Insights into Mental Disorders through Brain Imaging and High-Performance Computing
Health and Biomedical Sciences,
Gaining Deeper Insights into Mental Disorders through Brain Imaging and High-Performance Computing

Researchers from NUS are leveraging supercomputing to develop better strategies for prevention and treatment to mitigate the impact of mental illness. The human brain is a marvel…

Enhancing the safety of electric vehicles through HPC
Urban Solutions and Sustainability,
Enhancing the safety of electric vehicles through HPC

Researchers from NUS tap on supercomputing to simulate the multi-physical processes of lithium-ion batteriesin order to develop cooling strategies for more advanced battery…

Keeping drones safe in urban airspaces
Urban Solutions and Sustainability,
Keeping drones safe in urban airspaces

Researchers from NTU tap on high performance computing to identify hazardous airspaces through urban weather simulations in order to facilitate effective route planning and…

Accelerating electric vehicles research through HPC
Advanced Manufacturing and Engineering,
Accelerating electric vehicles research through HPC

Researchers from A*STAR IHPC leverage supercomputing resources to improve the performance of lithium-ion battery technology With the ever-increasing demand in energy storage…

Leveraging machine learning and supercomputers to accelerate new materials development
Advanced Manufacturing and Engineering,
Leveraging machine learning and supercomputers to accelerate new materials development

Researchers from NUS utilise high performance computing resources to accelerate the discovery and development of new materials. The development of novel functional materials has…

Enhancing Weather Prediction in Singapore: Leveraging Climate Model Simulations for Precision
Urban Solutions and Sustainability,
Enhancing Weather Prediction in Singapore: Leveraging Climate Model Simulations for Precision

Researchers from NUS Tropical Marine Science Institute are leveraging supercomputing to fine-tune Weather Research and Forecasting (WRF) Model and downscale hundreds of years of…

Advancing Drug Discovery Research using NSCC HPC resources
Health and Biomedical Sciences,
Advancing Drug Discovery Research using NSCC HPC resources

Researchers from Nanyang Technological University (NTU) are applying variational graph encoders as an effective generalist algorithm in computer-aided drug design (CADD)….

Using Digital Twin Technology to Optimise the Industrial 3D Printing Process
Advanced Manufacturing and Engineering,
Using Digital Twin Technology to Optimise the Industrial 3D Printing Process

Researchers from the Institute of High-Performance Computing (IHPC) are utilizing supercomputers to create a digital twin that furnishes users with comprehensive information…

Improving Singapore’s Food Security
Urban Solutions and Sustainability,
Improving Singapore’s Food Security

Researchers from the National University of Singapore are creating indoor-adapted crops to increase Singapore’s food production, with the help of NSCC Singapore’s HPC…